This site is intended for healthcare professionals

2288 pages added, reviewed or updated during the last month (last updated: 19/4/2021)

2288 pages added, reviewed or updated during the last month (last updated: 19/4/2021)


Medical search

regulation

FREE subscriptions for doctors and students... click here
You have 3 more open access pages.

The regulation of glycogen synthase is best considered in terms of:

  • hepatic enzyme regulation
  • skeletal muscle regulation

The key differences between the sites are:

  • hepatic glycogen synthase is more closely related to the intracellular glucose concentration, which is in equilibrium with the plasma glucose concentration, than skeletal muscle glycogen synthase
  • hepatic glycogen synthase is modulated more closely by both glycogen and insulin
  • skeletal glycogen synthase is more sensitive to changes in intracellular calcium concentration

Glycogen synthase acts in opposition to glycogen phosphorylase; the interaction between the two physiological antagonists is considered in the submenu.

Last reviewed 01/2018

Links: