Colorectal carcinoma is a term used to refer to cancerous growths of the colon, rectum and the appendix (1).
Majority of colorectal cancers arise from adenomatous polyps most of which are benign but a few may develop into cancer overtime (1).
Colorectal cancer (cancer of the colon or rectum, or bowel cancer) is the fourth most common cancer in the UK, with over 41,000 new cases diagnosed each year according to Cancer Research UK (3).
Most of the tumours are seen in the left side of colon. The percentage distribution of cases within the large bowel in Great Britain between the years 2007-2009 is as follows:
Much epidemiologic data for these two carcinomas have been grouped, but other aspects of the two diseases differ sufficiently that the two are discussed individually.
Survival rates have improved over time, with almost 60% of people diagnosed with colorectal cancer surviving for at least 5 years (3)
People with Lynch syndrome have an increased risk of colorectal cancer, with lifetime risk estimated to be between around 50% to 80% (3):
People who have been treated for colorectal cancer may have long-term side effects of their treatments. For example, low anterior resection syndrome can have major impact on quality of life and daily living, and it affects around 40% of those who have undergone sphincter-preserving surgery for rectal cancer (3).
Last edited 02/2020