Maturity onset diabetes of the young (MODY) is a heterogeneous group of monogenic disorders distinct from type 1 (insulin-dependent) and type 2 (noninsulin-dependent) diabetes (1,2).
The condition was first described by Tattersall in 1974–1975, a familial form of non-insulin dependent diabetes which showed autosomal dominant inheritance which presented before the age of 25 years (1,2). The molecular genetic basis of MODY was subsequently recognised in the 1990s and mutations in 10 different genes have been identified so far (2).
Prevalence of MODY is unknown but the minimum UK population prevalence of all MODY subtypes is estimated to be 68-108 cases per million.
Last edited 09/2020 and last reviewed 02/2021