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2437 pages added, reviewed or updated during the last month (last updated: 22/4/2021)


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Holt-Oram syndrome

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Holt-Oram syndrome is the occurrence of an atrial septal defect, particularly secundum defects, with:

  • other cardiac defects
  • skeletal defects of the upper limb
  • hypoplasia of clavicles

It is inherited in an autosomal dominant manner.

Last reviewed 01/2018

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