Triglyceride formation first requires the substrates, fatty acids and monoacylglycerol, to enter into the cell. For intestinal epithelial cells, this occurs through the processes of micelle absorption after digestion of dietary triglycerides by gastrointestinal lipases. For peripheral cells, the substrates enter after digestion of lipoprotein triglycerides by lipoprotein lipase enzymes on the surface of endothelia.
The steps involved include:
Last reviewed 03/2021