This site is intended for healthcare professionals

2635 pages added, reviewed or updated during the last month (last updated: 16/4/2021)

2635 pages added, reviewed or updated during the last month (last updated: 16/4/2021)


Medical search

triglyceride formation

FREE subscriptions for doctors and students... click here
You have 3 more open access pages.

Triglyceride formation first requires the substrates, fatty acids and monoacylglycerol, to enter into the cell. For intestinal epithelial cells, this occurs through the processes of micelle absorption after digestion of dietary triglycerides by gastrointestinal lipases. For peripheral cells, the substrates enter after digestion of lipoprotein triglycerides by lipoprotein lipase enzymes on the surface of endothelia.

The steps involved include:

  • conversion of fatty acids to acyl-CoA residues by acyl-CoA synthetase enzyme
  • combination of monoacylglycerol with acylCoA by acylglycerol transferase
  • combination of resulting diacylglycerol with acylCoA by diacylglycerol transferase enzyme to give triglyceride

Last reviewed 03/2021

Links: