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- in practice systolic blood pressure should be regarded as more important
than diastolic blood pressure (1)
- however, in general, there is a high correlation between systolic and diastolic
blood pressure. Also both have been shown to be important risk factors for
cardiovascular disease (2)
- outcome trials of antihypertensive therapy based on thresholds of systolic
(3) and diastolic blood pressure (4) have shown similar reductions in cardiovascular
- (1) British Hypertension Society guidelines for hypertension management
1999: summary. BMJ (1999), 319, 630-35.
- (2) Stamler J, Stamler R, Neaton JD (1993). Blood pressure, systolic and
diastolic and cardiovascular risks. US population data. Arch Intern Med, 153,
- (3) SHEP Cooperative Research Group (1991). Prevention of stroke by antihypertensive
drug treatment in older persons with isolated systolic hypertension. Final
results of the Systolic Hypertension in the Elderly Program (SHEP). JAMA,
- (4) Gueyffier F et al. Effect of antihypertensive drug treatment on cardiovascular
outcomes in women and men. A meta-analysis of individual patient data from
randomised controlled trials. Ann Intern Med, 126, 761-67.
Last reviewed 01/2018