Renal biopsy may be diagnostic in a patient with the nephrotic syndrome:
In adults renal biopsy is performed unless:
In cases of drug-induced nephrotic syndrome the drug is withdrawn; a biopsy is performed only if the patient fails to improve.
Because more than 75% of cases of paediatric nephrotic syndrome are caused by minimal change disease, children are given a trial of steroids unless there are features suggestive of another cause such as:
Last reviewed 01/2018