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2256 pages added, reviewed or updated during the last month (last updated: 21/4/2021)

2256 pages added, reviewed or updated during the last month (last updated: 21/4/2021)


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IgA deficiency

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Virtual absence of serum and secretory IgA, and occasionally of IgG2 and IgG4 is relatively common, affecting 1 in 600 people. It may be familial or may be acquired following toxoplasmosis, measles, or other viral infections.

The basic defect is a failure of maturation of IgA positive B cells. Immature forms are present in normal numbers.

Last reviewed 01/2018

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