This site is intended for healthcare professionals

2630 pages added, reviewed or updated during the last month (last updated: 18/4/2021)

2630 pages added, reviewed or updated during the last month (last updated: 18/4/2021)


Medical search

POEMS syndrome

FREE subscriptions for doctors and students... click here
You have 3 more open access pages.

POEMS is an acronym for:

  • polyneuropathy:
    • slow onset of mixed motor and sensory polyneuropathy
    • peripheral nerve demyelination with some axonal degeneration

  • organomegaly:
    • hepatosplenomegaly

  • endocrinopathy:
    • gynaecomastia
    • secondary amenorrhoea
    • diabetes mellitus
    • hypothyroidism

  • monoclonal protein

  • skin changes:
    • hyperpigmentation
    • hypertrichosis
    • skin thickening

The underlying pathology is usually an osteosclerotic myeloma. Radiographic surveys often reveal a single osteosclerotic lesion in the spine or proximal long bones.

Last reviewed 01/2018

Links: