Deep vein thrombosis, a subset of venous thromboembolism (VTE), occurs in normal veins, usually the deep calf veins of the leg and propagates more proximally (1).
It is generally thought of as a complication of surgery or illness.
However, a number of situations predispose an individual to a deep vein thrombosis, and are encapsulated in Virchow's Triad (blood hypercoagulability, endothelial damage and venous stasis) (4).
The natural history is one of gradual breakdown of the thrombus with recanalisation. Damage to the valves may produce deep venous incompetence.
DVT is a usual precursor of both fatal PE and post-thrombotic syndrome (PTS) (4).
Last edited 05/2020 and last reviewed 01/2021