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Cholesterol-lowering therapy is an area of medicine that has prompted heated
debate and a great deal of confusion.
Hypercholesterolaemia treatment can
be considered in terms of primary and secondary prevention of coronary heart disease.
general, the treatment of choice for raised cholesterol is a statin.
state that (1):
- before offering lipid modification therapy for primary
prevention, all other modifiable CVD risk factors should be considered and their
management optimised if possible. Baseline blood tests and clinical assessment
should be performed, and comorbidities and secondary causes of dyslipidaemia should
be treated. Assessment should include:
- smoking status
- blood pressure
- body mass index or other measure
- fasting total cholesterol, LDL cholesterol, HDL cholesterol
and triglycerides (if fasting levels are not already available)
- renal function
- liver function (transaminases)
- thyroid-stimulating hormone (TSH) if dyslipidaemia is present
Last reviewed 01/2018