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exchange transfusion

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Exchange transfusion will give an urgent reduction in the serum levels of bilirubin, especially where the hyperbilirubinaemia is the result of rhesus isoimmunisation.

For treatment threshold graphs for phototherapy and exchange transfusion for babies with gestational ages from 23 weeks to 38 weeks or more

Consensus-based bilirubin thresholds for management of babies 38 weeks or more gestational age with hyperbilirubinaemia

Table: An exchange transfusion should be performed unless the bilirubin level falls below threshold while the treatment is being prepared

Age (hours) Bilirubin measurement (micromol/litre)
0 > 100
6 > 150
12 > 200
18 > 250
24 > 300
30 > 350
36 > 400
42 > 450
48 > 450
54 > 450
60 > 450
66 > 450
72 > 450
78 > 450
84 > 450
90 > 450
96+ > 450

 

Reference:

Last reviewed 01/2018

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