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This is a common cause of chronic renal failure in Europe. It is the result of chronic high intake of simple analgesics over a period of several years.
The nephropathy is characterised by chronic tubulo- interstitial nephritis and renal papillary necrosis.
Non-steroidal anti-inflammatory drugs (NSAIDs) are the most frequent cause of drug induced renal damage in clinical practice (1).
Analgesic nephropathy is much more common in women than in men (2). Typically analgesic nephropathy results in chronic renal failure in late middle age.
Analgesic nephropathy is associated with an increased incidence of urothelial maligancy (1,2,3,4).
Notes (4):
Reference:
Last reviewed 01/2018
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