This site is intended for healthcare professionals

2499 pages added, reviewed or updated during the last month (last updated: 18/4/2021)

2499 pages added, reviewed or updated during the last month (last updated: 18/4/2021)


Medical search

inotropes

FREE subscriptions for doctors and students... click here
You have 3 more open access pages.

Inotropes can be divided into the following classes:

  • cardiac glycosides
  • catecholamines
  • phosphodiesterase inhibitors
  • calcium entry promoters - opposite of calcium channel blockers. Act on nitrendipine receptors. Good intropy in vitro, but in vivo, vasoconstriction precludes increase in mechanical activity.
  • calcium
  • calcium sensitizers - increase affininty of troponin for calcium (depressed by hypoxia and acidosis). These are a potential future developement, with the added potential advantage that they would not increase myoplasmic calcium, therefore perhaps less problem with arrhythmias.

Last reviewed 01/2018

Links: