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2625 pages added, reviewed or updated during the last month (last updated: 15/4/2021)


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pathology

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The core pathology in Parkinson's disease is:

  • degeneration of the dopaminergic nigrostriatal pathway
  • decrease in the striatal concentration of dopamine
  • presence of laminated inclusions - Lewy bodies - in neurons of the substantia nigra

Last reviewed 01/2018

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