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2630 pages added, reviewed or updated during the last month (last updated: 17/4/2021)


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epilepsy and Depo Provera

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NICE state that (1):

  • the use of additional barrier methods should be discussed with women and girls taking enzyme-inducing anti-epileptic drugs (AEDs) and oral contraception or having depot injections of progestogen

However FSRH guidance states with respect to depot medroxyprogesterone acetate (DMPA) or the levonorgestrel-releasing intrauterine system; used concurrently with enzyme-inducing AEDs

  • no interaction and no need for extra precautions

Reference:

  1. NICE (April 2018).The epilepsies: the diagnosis and management of the epilepsies in adults and children in primary and secondary care.
  2. Faculty of Sexual & Reproductive Healthcare Clinical Guidance.Clinical Guidance: Drug Interactions with Hormonal Contraception January 2018.

Last edited 08/2018 and last reviewed 03/2021

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