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2428 pages added, reviewed or updated during the last month (last updated: 23/4/2021)


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improving efficacy

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Chemotherapeutic drug efficacy can be improved by:

  • alternating non-cross resistant regimens
  • high dose therapy with rescue of normal tissues - eg autologous bone marrow transplant
  • optimum dose intensity - seen in retrospective data
  • improved scheduling - e.g. etoposide in small cell lung cancer
  • reduction in myelotoxicity - colony stimulating factors, stem cell infusions

Last reviewed 01/2018

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