This site is intended for healthcare professionals

2499 pages added, reviewed or updated during the last month (last updated: 19/4/2021)

2499 pages added, reviewed or updated during the last month (last updated: 19/4/2021)


Medical search

CREST syndrome

FREE subscriptions for doctors and students... click here
You have 3 more open access pages.

CREST - is a localised form of systemic sclerosis associated with a better prognosis. It comprises:

  • Calcinosis - palpable nodules in the hands due to calcific deposits in the subcutaneous tissue
  • Raynaud's phenomenon - ischaemia resulting in atrophy of the finger pulps
  • oEsophageal dysmotility - if absent, then CRST syndrome
  • Sclerodactyly - tightening of the skin of the fingers resulting in tapering
  • Telangiectasia - multiple, large and on the fingers

Tethering of the skin proximal to the wrists, on the legs or trunk suggests systemic sclerosis.

The features of the different forms of systemic sclerosis have been described (1):

Reference:

  • 1) Arthritis Research Campaign (2010). Topical Reviews - Systemic sclerosis and related disorders

Last reviewed 01/2018

Links: