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2693 pages added, reviewed or updated during the last month (last updated: 13/4/2021)


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pyruvate kinase

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Pyruvate kinase is an enzyme of the glycolytic pathway that converts phosphoenolpyruvate into pyruvate. It is a large enzyme with several subunits and binding sites; correspondingly, it is the target for regulation by several molecules.

It exists as 3 isoenzymes. The L isoenzyme predominates in hepatocytes; the M isoenzyme predominates in muscle.

Last reviewed 01/2018

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