Motor neurone disease most commonly presents with upper or lower motor neurone signs, or a mixture of the two. The disease affects limb muscles or those supplied by cranial nerves.
Motor neurone disease (MND) is a neurodegenerative condition that affects the brain and spinal cord. MND is characterised by the degeneration of primarily motor neurones, leading to muscle weakness.
disease is of unknown aetiology and results in pathological changes in the anterior horn cells, the motor nuclei of the medulla, and the corticospinal tracts.
Every person with MND has an individual progression of the disease
Poor prognostic factors (1) - when planning care take into account the following prognostic factors, which are associated with shorter survival if they are present at diagnosis:
Last reviewed 01/2018