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2625 pages added, reviewed or updated during the last month (last updated: 15/4/2021)


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ceruloplasmin

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This is a copper containing protein which normally binds 90% of the copper present in plasma. It is not a copper transport protein but mirrors changes in serum levels.

The normal plasma level is 1-2.7 micromoles per litre.

Serum ceruloplasmin is reduced in:

  • Wilson's disease
  • malnutrition
  • nephrotic syndrome

It is increased in:

  • pregnancy
  • oestrogen containing contraceptives
  • acute infection
  • some types of chronic liver disease
  • malignancy

Note that reference ranges may vary with different laboratories.

Last reviewed 01/2018

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