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2288 pages added, reviewed or updated during the last month (last updated: 19/4/2021)


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clinical features and consequences

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In liver cirrhosis, there may be no stigmata of live disease if the patient is 'compensated'. Otherwise clinical features may include:

  • symptoms:
    • lethargy
    • itch, especially in primary biliary cirrhosis
    • fever
    • weight loss
    • swelling of abdomen and ankles.

  • signs:
    • jaundice
    • finger clubbing
    • leuconychia
    • palmar erythema
    • bruising
    • spider naevi
    • parotitis
    • sexual changes:
      • in males: gynaecomastia, reduced body hair
      • in females: erratic menstruation and breast atrophy;
    • hepatomegaly
  • splenomegaly

Also, liver cirrhosis can cause:

  • portal hypertension
  • transudate ascites
  • Cruveilhier-Baumgarten syndrome
  • oesophageal varices

Last reviewed 01/2018

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