Lymphogranuloma venerum is a tropical sexually transmitted disease caused by Chlamydia trachomatis (L1,L2,L3).
It is endemic in Africa, India, SE Asia, South America and the Caribbean, with men affected more commonly than women, principally between the age 20 to 30 years.
There are three stages to the disease:
Diagnosis is by serology and intradermal skin test with LGV antigen - Frei's test.
The condition spontaneously remits, but can be treated with tetracyclines or erythromycin. Patients with LGV may also harbour other sexually transmitted disease including syphilis.
Last reviewed 01/2018