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2693 pages added, reviewed or updated during the last month (last updated: 14/4/2021)


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ACEI and low sodium

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  • angiotensin converting enzyme (ACE) inhibitors have been associated with dilutional hyponatremia (1,2,3):

    • ACE inhibitors alone can precipitate hyponatremia without co-administration of thiazide diuretics

    • hyponatremia induced by ACE inhibitors appears to be dilutional and is accompanied by features of SIADH

    • discontinuing the ACE inhibitor leads to resolution of the hyponatremia.

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Last reviewed 01/2018

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