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Differential diagnosis

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

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The diagnosis of angina usually assumes that the cause is atherosclerosis. Other causes of cardiogenic chest pain include: (1)

  • aortic stenosis
  • hypertrophic cardiomyopathy
  • mitral valves prolapse (Barlow's syndrome)
  • aortic dissection
  • pulmonary embolism
  • coronary artery spasm

Pain similar to angina may be caused by:

  • gastrointestinal disease:
    • gastro-oesophageal acid reflux
    • oesophagitis
    • biliary colic
    • gastritis
    • pancreatitis
  • musculoskeletal pain:
    • Bornholm's syndrome
    • Tietze's syndrome
  • psychiatric
    • anxiety disorders - hyperventilation, panic disorder o affective disorder - depression

Reference:

1. Gulati M, Levy PD, Mukherjee D, et al. 2021 AHA/ACC/ASE/CHEST/SAEM/SCCT/SCMR Guideline for the evaluation and diagnosis of chest pain: A report of the American College of Cardiology/American Heart Association joint committee on clinical practice guidelines. Circulation. 28 Oct 2021

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