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Aspirin in angina

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In chronic stable angina the use of aspirin reduces the risk of myocardial infarction, stroke, and death. A dose of 75 mg to 162 mg once daily is recommended lifelong in all patients with stable angina. In aspirin-intolerant patients, clopidogrel 75 mg once daily is recommended.

Unstable angina falls under the umbrella term ‘acute coronary syndrome’ (ACS). In all patients with ACS, an oral antiplatelet agent should be used (such as clopidogrel, prasugrel or ticagrelor) in conjunction with aspirin to reduce the risk of a major cardiovascular event. For patients with non-ST-segment elevation ACS (NSTE-ACS) undergoing PCI, either ticagrelor or prasugrel is recommended.

Reference

  1. NICE. Acute coronary syndromes. NICE guideline NG185. Published November 2020

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