Class I drugs in paroxysmal atrial fibrillation
Flecainide is effective in reducing the recurrence of symptomatic paroxysmal atrial fibrillation. Adverse effects are common but usually tolerable. There is concern about increased mortality with flecainide especially following myocardial infarction.
Propafenone may also be effective in paroxysmal atrial fibrillation.
Reference
- NICE. Atrial fibrillation: diagnosis and management. NICE guideline NG196. Published April 2021, last updated June 2021
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