Acute vs. non-acute porphyria
The acute porphyrias include:
- acue intermittent porphyria
- hereditary coproporphyria
- variegate porphyria
Non-acute porphyrias include:
- porphyria cutanea tarda
- congenital porphyria
- erythropoietic protoporphyria
The accumulation of delta-aminolevulinate and porphobilinogen in acute porphyrias results in the characteristic abdominal pain and neuropsychiatric features.
Accumulation of specific uro- and coproporphyrins in the abscence of porphobilinogen excess results in the features of non-acute porphyria, particularly photosensitivity.
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