Digoxin in paroxysmal atrial fibrillation
The use of digoxin in paroxysmal atrial fibrillation is detrimental, resulting in longer and more frequent episodes.
Furthermore, the heart rate during a paroxysm of atrial fibrillation is poorly controlled by digoxin. Therefore the use of digoxin in the management of paroxysmal atrial fibrillation is better avoided (1,2).
Reference:
- (1) The Digitalis Investigation Group (1997). The effect of digoxin on mortality and morbidity in patients with heart failure. NEJM, 336, 25-33.
- (2) British Heart Foundation (Factfile 7/2001). The use of digoxin.
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