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The Long-term Intervention with Pravastatin in Ischaemic Disease (LIPID) study was a double-blind randomised placebo controlled study of the effect of pravastatin in patients with a history of myocardial infarction or unstable angina who had a broad range of cholesterol levels.
Patients randomised to pravastatin showed a 20-30% relative risk reduction for a range of cardiovascular including:
This study suggests that any patient with a previous diagnosis of unstable angina or myocardial infarction should receive a statin.
For every 1000 patients treated for 6.1 years the following end-points were avoided: