Laboratory events in monitoring oral gold

Event: Value Action

Leucopaenia <3.5*10^9/l Stop & seek advice

Neutropaenia <2.5*10^9/l Stop & seek advice

Thrombocytopaenia <150*10^9/l Stop & seek advice

Sequential falls >10% on Stop & seek advice in WCC or PMNs 3 occasions

Sequential falls >10% on Stop unless falls are from in platelets 3 occasions a high level, which is a response to treatment

Haematuria trace or + Continue drug

Haematuria ++ or +++ Stop drug, check MSU, consider other causes, seek advice

Proteinuria trace or + Continue drug

Proteinuria ++ or +++ Stop drug, check MSU, 24 hour urinary protein seek advice