Cautions and contraindications
Contraindications include:
- moderate or severe renal impairment
- impaired hepatic function
- severe hypoproteinaemia
- known immunodeficiency
- bone marrow dysfunction, leucopenia, neutropenia, anaemia, thrombocytopenia - secondary to causes other than RA
- serious infections
- known hypersensitivity to leflunomide
- women who are pregnant or who are breast feeding - after stopping treatment the manufacturer advises that a woman should wait for 2 years before trying to conceive
- this drug has not been tested in people under 18 years old and therefore is contraindicated in patients below this age
Check the manufacturer's prescribing information before prescribing this drug.
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