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Leukotriene C4

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

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Leukotrienes C4 to E4 are produced from leukotriene A4 by sequential amino acid substitution. They are thought to be intimately involved in inflammation. General effects include:

  • bronchoconstriction
  • vasoconstriction
  • increased post-capillary permeability with subsequent oedema
  • smooth muscle constriction

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