Nail-patella syndrome

Nail-patella syndrome also known as Iliac Horn syndrome, Hereditary Onychoostedysplasia, Fong Disease or Turner-Kiser syndrome is a congenital nail disorder with an autosomal dominant inheritance (1).

The disease is characterized by

• nail and elbow dysplasia
• patellar aplasia or hypoplasia
• iliac horns (1).

Other involved sites include

• kidneys
• eyes - open-angle glaucoma, cloverleaf dark pigmentation of the iris, micro and sclerocornea, and cataracts
• central and/or peripheral nervous systems - peripheral polyneuropathy and vasomotor dysfunction (uncommon) (1)

Reference:

• (1) Hennessey TA et al.Nail-Patella syndrome: a case report and anesthetic implications.Canadian Journal of Anesthesia2007; 54:835-839