Predisposing genes
Genetic loci associated with keloid scarring
The following genes have been associated with keloid scarring:
- TGF-beta 1 and 2 isoforms
- TGF-beta 3 (1)
- HLA-B14
- HLA-B21
- HLA-Bw16
- HLA-Bw35
- HLA-DRB1 (2)
- HLA-DR5
- HLA-DQw3
- blood group A
Ref:
(1) Bayat A, Walter JM, Bock O et al. Br J Plast Surg (2005); 58(7): 914-921.
(2) Brown JJ, Ollier WE, Arscott G, Bayat A. Clin Exp Dermatol (2010); 35(3): 305-310.
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