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Skin prick testing in urticaria

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

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Skin prick testing (SPT)

  • allergic reactions to foods are rarely the cause of chronic urticaria but patients are often referred to hospital in the belief that foods are responsible
    • a practical approach is to start by excluding an atopic diathesis by undertaking skin prick tests (SPTs) to a panel of aeroallergens
      • if negative, this significantly reduces the likelihood of an IgE-mediated allergic reaction to foods and other allergens
  • additional skin testing can also be helpful to some of the foods that the patient suspects as the cause of their urticaria

  • the sight of a negative SPT helps to reassure the patient that allergy is not the cause of their symptoms and may contribute to improved concordance with long-term antihistamines
    • however, foods may be responsible for the symptoms of acute intermittent urticaria, for example wheat followed by exercise can cause urticaria/angio-oedema and even anaphylaxis
      • in this situation the patient is often atopic and has a positive SPT and/or specific IgE to the implicated food

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