Factors associated with a higher risk of recurrence
There are several factors that may have an effect on recurrence rate including histological sub-type, other histological features, site, and other patient and tumour features.
Histological sub-type
- morphoeic – linear groups of cancer cells with surrounding scarring; clinically this causes a thickened and hardened skin
- infiltrating – like morphoeic but with less scarring
- micronodular – very small groups of cancer cell
- basosquamous carcinoma – a skin cancer with both basal and squamous elements
Histological features
- perineural invasion
- invasion below dermis
Sites
- nose and paranasal folds
- periocular
- ears
- scalp and temples
- lips
Other factors
- size > 2 cm
- immunosuppression
- genetic disorders such as Gorlin’s syndrome
- previously treated lesion
Reference:
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