Aetiology
- 95% of cases are due to a growth hormone secreting pituitary adenoma
- less than 3% of cases are due to ectopic GHRH production - carcinoid tumours especially bronchial, pancreatic islet tumours or adrenal tumours
- less than 2% of cases result from ectopic GH secreting pancreatic islet tumours
The condition may arise as part of the type I multiple endocrine neoplasia syndrome.
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