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Clinical uses

Authoring team

ACTH is used to:

  • investigate adrenal cortical insufficiency:
    • an intramuscular dose is given
    • the change in baseline plasma cortisol is monitored
  • treat:
    • on occasion, an underactive adrenal cortex that is not producing enough corticosteroid
    • rarely, to treat inflammatory disorders rather than using exogenous glucocorticoids which would otherwise have deliterious catabolic side effects; this may be important in children

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