Generalised peritonitis can be caused by the following:
any cause of localised peritonitis if left for long enough
perforation of a viscus causing generalised peritoneal irritation, e.g. stomach, colon, gall bladder, enzymatic discharge in acute pancreatitis
chemical peritonitis may be caused by any foreign substance introduced into the peritoneum, for example talcum powder from operating gloves
spreading intraperitoneal infection, e.g. faecal contamination following bowel perforation, rupture of an intra-abdominal abscess, anastomotic leak, trauma, surgery
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