Features of pituitary tumour
A growth hormone secreting pituitary adenoma may produce the following clinical features locally:
- headache
- visual field defects - most commonly a superior bi-temporal quadrantanopia, progressing to a bi-temporal hemianopia
- cerebrospinal fluid rhinorrhoea due to inferior extension of the tumour
- III and more rarely IV and VI nerve palsies due to lateral extension of the tumour
- FSH / LH, ACTH and TSH deficiencies due to pressure on adjacent normal pituitary cells. Deficiency of FSH/LH is most common producing hypogonadism. ACTH and TSH deficiencies tend only to occur in longstanding cases.
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