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Diabetes insipidus

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

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This is the inability to produce a concentrated urine due to:

  • a deficiency of antidiuretic hormone (ADH) (cranial diabetes insipidus), or,
  • renal resistance to ADH (renal diabetes insipidus)

Patients present with polydipsia and polyuria.(1).


  1. Levy M, Prentice M, Wass J. Diabetes insipidus. BMJ. 2019 Feb 28;364:l321. doi: 10.1136/bmj.l321.

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