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Medical conditions associated with an increased prevalence of testosterone defiency

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

Authoring team

Conditions associated with an increased prevalence of TD

Medical conditions associated with an increased prevalence of TD:1-5

Andrological and endocrinological

Metabolic diseases

Cardiovascular diseases

Other chronic diseases

Pituitary disease

Delayed puberty





Metabolic syndrome

Type 2 diabetes mellitus




Atrial fibrillation

Coronary artery disease

Cerebrovascular disease

Chronic heart failure

End-stage renal disease

Cirrhosis Cancer


Chronic obstructive pulmonary disease

Rheumatoid arthritis



  • Khera M, Adaikan G, Buvat J, et al. Diagnosis and Treatment of Testosterone Deficiency: Recommendations From the Fourth International Consultation for Sexual Medicine (ICSM 2015). J Sex Med 2016;13:1787-1804.
  • Dohle GH, Arver S, Bettochi C et al. Guidelines on Male Hypogonadism. European Association of Urology 2017. Available at: (Accessed May 2018).
  • Bhasin S et al. Task Force, Endocrine Society. Testosterone therapy in men with androgen deficiency syndromes: An Endocrine Society clinical practice guideline. J Clin Endocrinol Metab 2010;95:2536-59.
  • Lunenfeld B, Mskhalaya G, Zitzmann M, et al. Recommendations on the diagnosis, treatment and monitoring of hypogonadism in men. Aging Male 2015;18:5-15.
  • Hassan J, Barkin J. Testosterone deficiency syndrome: benefits, risks and realities associated with testosterone replacement therapy. Can J Urol 2016;23:20-30.

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