Growth hormone deficiency

Growth hormone deficiency (GHD) is a rare disorder resulting in:

• short stature in untreated children
• metabolic and psychological morbidity in adults

GHD - defined as suboptimal GH secretion - includes a group of different aetiological disorders. It may be isolated (IGHD) or combined with other anterior and/or posterior pituitary hormone deficiencies.

Combined pituitary hormone deficiency (CPHD) is defined as a deficiency in two or more pituitary hormones.

GHD may be congenital or acquired, sporadic or familial.

Reference

1. Ranke MB. Short and Long-Term Effects of Growth Hormone in Children and Adolescents With GH Deficiency. Front Endocrinol (Lausanne). 2021 Sep 1;12:720419.