Lactic acidosis
Lactic acid is the end product of anaerobic glycolysis.
Lactate is in equilibrium with pyruvate, anaerobic conditions increasing the normal 10:1 lactate:pyruvate ratio.
The concentration of lactate in the blood is usually less than 1 mM, but rise physiologically after severe exercise to as high as 10 mM.
Lactic acidosis should be suspected in patients with a high anion gap metabolic acidosis, when uraemia and ketoacidosis have be excluded.
Related pages
Create an account to add page annotations
Add information to this page that would be handy to have on hand during a consultation, such as a web address or phone number. This information will always be displayed when you visit this page