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Clinical features

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

Authoring team

This form of the condition has the most severe clinical manifestations.

  • development of vomiting and poor feeding during the first week of life, after being normal at birth.
  • the child then becomes lethargic and falls into a coma over the next few days.
  • there may be convulsions
  • hypoglycamia may develop

On examination there is:

  • increased tone, rigid muscles and severe opisthotonus, which may alternate to periods of flaccidity.

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The content herein is provided for informational purposes and does not replace the need to apply professional clinical judgement when diagnosing or treating any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions.

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