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Ten percent rule

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Phaeochromocytomas may be referred to as the 10% tumour:

  • 10% are extra-adrenal, most commonly, in the organ of Zuckerkandl, located in the aortic bifurcation. Less than 1% are extra-abdominal
  • 10% are bilateral, increasing to 70% in familial cases
  • 10% are malignant, but the risk of malignancy in women is three fold that in men
  • 10% are multiple
  • 10% occur in children, but 25-30% of children have extra-adrenal and/or bilateral tumours

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