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ST John's wort and theophylline

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

Authoring team

St John's wort (SJW) interacts with theophylline and may cause reduced theophylline levels.

Suggested management of patients already taking SJW preparations:

  • check theophylline levels and stop SJW

  • note that there may be an increase in theophylline levels on stopping SJW

  • it may be necessary to adjust the theophylline dose


  • CEM/CMO/2000/4

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