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Thiazide in heart failure

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

Authoring team

  • may be used as initial treatment in heart failure e.g. cyclopenthiazide 0.25-0.5 mg/24h PO

The ALLHAT data revealed that chlorthalidone was superior to calcium channel blockers and, at least in the short term, angiotensin-converting enzyme inhibitors in preventing heart failure in hypertensive individuals.


  1. Davis BR et al. Role of diuretics in the prevention of heart failure: the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial. Circulation. 2006 May 9;113(18):2201-10

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