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The tricarboxylic acid cycle can produce the equivalent of 12 molecules of ATP per molecule of acetyl-CoA oxidized. This is produced as follows:
Via the electron transport chain, each molecule of NADH produces 3 molecules of ATP. The FADH2 coenzyme of succinate dehydrogenase can produce 2 molecules of ATP.
Overall, counting the 3 molecules of ATP for each reaction that pyruvate dehydrogenase catalyzes, the complete oxidation of 1 molecule of glucose via glycolysis and the tricarboxylic acid cycle can yield 38 molecules of ATP.
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